<strike id="aqcwk"></strike>
<strike id="aqcwk"></strike>
  • 
    
  •   設(shè)為主頁(yè) 加入收藏 English
     
     
     
     新聞動(dòng)態(tài)
     行業(yè)動(dòng)態(tài)
     展會(huì)信息
     誠(chéng)聘英才
     
     

    Enhanced near-infrared photoacoustic imaging of silica-coated rare-earth doped nanoparticles

    發(fā)布時(shí)間:2017-03-23  點(diǎn)擊次數(shù):1892  新聞來(lái)源:
     

    作者 Yang Shenga, f, Lun-De Liaob, c, Aishwarya Bandlac, d, Yu-Hang Liuc, e, Jun Yuanc, Nitish Thakorc, d, e, Mei Chee Tana

    a Engineering Product Development, Singapore University of Technology and Design, 8 Somapah Road, Singapore 487372, Singapore

    b Institute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, 35 Keyan Rd., Zhunan Town, Miaoli County 35053, Taiwan, ROC

    c Singapore Institute for Neurotechnology (SINAPSE), National University of Singapore, 28 Medical Drive, #05-COR, Singapore 117456, Singapore

    d Department of Biomedical Engineering, National University of Singapore, 21 Lower Kent Ridge Rd, Singapore 119077, Singapore

    e Department of Electrical and Computer Engineering, National University of Singapore, 21 Lower Kent Ridge Rd, Singapore 119077, Singapore

    f School of Materials Science and Engineering, Changzhou University, Changzhou, Jiangsu 213164, PR China

     

    摘要:Near-infrared photoacoustic (PA) imaging is an emerging diagnostic technology that utilizes the tissue transparent window to achieve improved contrast and spatial resolution for deep tissue imaging. In this study, we investigated the enhancement effect of the SiO2 shell on the PA property of our core/shell rare-earth nanoparticles (REs) consisting of an active rare-earth doped core of NaYF4:Yb,Er (REDNPs) and an undoped NaYF4 shell. We observed that the PA signal amplitude increased with SiO2 shell thickness. Although the SiO2 shell caused an observed decrease in the integrated fluorescence intensity due to the dilution effect, fluorescence quenching of the rare earth emitting ions within the REDNPs cores was successfully prevented by the undoped NaYF4 shell. Therefore, our multilayer structure consisting of an active core with successive functional layers was demonstrated to be an effective design for dual-modal fluorescence and PA imaging probes with improved PA property. The result from this work addresses a critical need for the development of dual-modal contrast agent that advances deep tissue imaging with high resolution and signal-to-noise ratio.

     
     
    上海市普陀區(qū)嵐皋路567號(hào)1108-26室 電話:021-62665073 400-718-7758 傳真:021-62761957 聯(lián)系郵箱:info@bicchina.com
    美國(guó)布魯克海文儀器公司上海代表處 版權(quán)所有  管理登陸 ICP備案號(hào):滬ICP備19006074號(hào)-2 技術(shù)支持:化工儀器網(wǎng)
    主站蜘蛛池模板: 无码日韩精品一区二区免费| 国产麻豆精品一区二区三区v视界| 亚洲一区二区三区国产精品| 亚洲精品国产精品乱码在线观看| 国产产无码乱码精品久久鸭| 麻豆国内精品欧美在线| 成人无码精品1区2区3区免费看| 蜜臀AV无码国产精品色午夜麻豆| 国产精品亚洲午夜一区二区三区| 久久久久久国产精品无码下载| 九九热在线视频观看这里只有精品| 在线精品无码字幕无码AV| 国产精品日韩欧美在线第3页| 国产精品igao视频网| 中文字幕精品久久久久人妻| 97久人人做人人妻人人玩精品| 国产精品美女久久久久久2018| 午夜在线视频91精品| 成人精品一区二区三区在线观看| 精品无码日韩一区二区三区不卡| 午夜精品久久久久9999高清| 国产在线精品一区免费香蕉| 国产成人精品无码片区在线观看| 亚洲一日韩欧美中文字幕欧美日韩在线精品一区二 | 中文字幕精品亚洲无线码一区应用| 国产成人精品曰本亚洲79ren| 精品免费tv久久久久久久| 国产精品久线在线观看| 亚洲AV无码久久精品色欲| 四虎精品成人免费视频| 久久精品国产福利国产琪琪| 国产精品热久久无码av| 国产成人综合久久精品尤物| 四虎永久在线精品884aa下载| 国产精品毛片久久久久久久| 91精品视频网站| 大伊香蕉精品视频在线导航| 99re热视频这里只精品| 500av大全导航精品| 国产精品无码AV一区二区三区| 亚洲av永久无码精品表情包|